Genetic findings further understanding of bone strength, study says

13 Sep 2017

A study looking into genetics and osteoporosis has found 153 previously unknown genes associated with bone mineral density.

 The findings  - published in the journal Nature Genetics – were made possible by use of UK Biobank which provides a considerably  larger sample for genetic studies compared to previous investigations.

The discovery could pave the way for genetic testing for osteoporosis and possible new treatments.

Jon Tobias, Professor of Rheumatology at the University of Bristol and one of the study’s authors, said the advances in the ability of genetic factors to predict bone strength suggests that genetic testing for osteoporosis “may become a reality in the foreseeable future” and may pave the way for new osteoporosis drugs.

“Our findings provide an important proof of principle that genome wide association mega analysis enable new mechanisms responsible for osteoporosis to be identified, possibly leading to new treatments for this condition.”

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