OUR CURRENT RESEARCH PROJECTS

Grant Schemes

Project Grant: A high-quality 2-4 year project designed to answer key questions related to osteoporosis.

Innovative Award: A 12 month (maximum) pilot project to help generate data required for an application to a larger funding organisation/research council.

Linda Edwards Memorial PhD Studentship: A 3-4 year project enabling an outstanding science graduate to study for a PhD and embark on a research career in osteoporosis.

     

Project Grants

Osteoprotegerin antibodies in the pathogenesis and treatment of severe osteoporosis

  • Principal Investigator: Dr Philip Riches, University of Edinburgh
  • In some people severe osteoporosis can develop due to the presence of antibodies which attack bone. This study aims to understand if the presence of these antibodies influences a person’s response to treatment and therefore help develop personalised patient treatment plans.

The epidemiology of fragility fractures in the United Kingdom

  • Principal Investigator: Professor Tjeerd van Staa and Professor Nick Harvey, University of Southampton
  • This study aims to answer questions related to the prevalence and impact of all types of fragility fractures in the UK, an issue which has not been addressed for 15 years.

The pathogenesis of distal forearm fractures in men: the Mr F Study

  • Principal Investigator: Miss Birgit Hanusch, James Cook University Hospital
  • Men who suffer a forearm fracture are twice as likely to further fracture compared to women. This study aims to identify the causes of these low trauma forearm fractures in men in order to prevent secondary fractures.

Comparative safety of anti-fracture therapies in the community and in specific groups of patients in the UK: a cohort study

  • Principal Investigator: Dr Daniel Prieto-Alhambra, University of Oxford
  • This project is the first of its kind to generate UK specific evidence to inform patients, physicians and commissioners within the NHS of the potential risks and benefits of drugs used for the prevention of bone fractures.

The additive effect of vitamin K supplementation and bisphosphonate on fracture risk in post-menopausal osteoporosis

  • Principal Investigator: Dr Geeta Hampson, Guys and St Thomas NHS Trust
  • Vitamin K is thought to help bone formation and this study aims to see whether it can enhance existing treatments when they are used in combination.

Clinical evaluation of a free vitamin D assay for the study of vitamin D status in those with or at risk of osteoporosis

  • Principal Investigator: Professor Richard Eastell, University of Sheffield
  • It is believed that active vitamin D levels can be measured more reliably in saliva rather than blood. This project aims to develop a new saliva based vitamin D test to help more accurately identify people at risk of osteoporosis due to vitamin D deficiency.

           

Innovative Awards

Effects of postural taping on pain and function following osteoporotic vertebral fractures - a pilot study

  • Principal Investigator: Professor Shea Palmer, University of West England
  • Investigation into whether a new taping device for the back can help improve pain, function and quality of life for people affected by osteoporotic spinal fractures.

Hip fracture risk model incorporating in situ bone activity and marrow adiposity

  • Principal Investigator: Dr Harish Datta, Newcastle University
  • Looking at whether information on bone and fat cell activity could provide an additional assessment tool that will help predicting the chances of breaking a bone.

              

Linda Edwards Memorial PhD Studentship

Influence of combined vitamin D supplementation and resistance exercise training on musculoskeletal health in frail older men and women

  • Principal Investigator: Dr Carolyn Greig, University of Birmingham
  • Investigating whether in older people a combination of vitamin D and resistance exercise can improve muscle and bone health.

The impact of geographic and socio-economic variation on the incidence of hip fracture, and upon death and recovery after hip fracture

  • Principal Investigator: Dr Celia Gregson, University of Bristol
  • The number of hip fractures and their outcomes varies across the UK due to healthcare inequalities. This study will identify the regions in the UK with the poorest outcomes and provide the evidence needed to improve local services and ensure high quality services for all hip fracture patients.

                             

WANT TO KNOW MORE ABOUT OUR RESEARCH PROJECTS?

Please contact us if you would like more information about the research studies listed

01761 473 125

Alternatively you can contact us via e-mail at research@nos.org.uk

CONTACT US

Dr Elaine Dennison, Chair of the NOS Research Grants Committee

We receive no government funding so all our research projects are only made possible thanks to the generous support of our members and donors.

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Professor Nicholas Harvey, NOS Research Grant Holder

The National Osteoporosis Society was awarded AMRC best practice in medical and health research in the 2015 peer review audit

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Young Scientist Prize 2014 Winner

An small grant awarded to an outstanding young investigator pursuing a career in osteoporosis in order for them to undertake an independent research project.

Dr. Fjóla Jóhannesdóttir, University of Cambridge

Dr. Fjóla Jóhannesdóttir is currently a research associate in the department of medicine at the University of Cambridge. She has a strong track record of research into osteoporosis and hip fractures, focusing on the determinants of bone strength as well as the mechanics of age-related bone fragility. Her goals are to improve the understanding of bone fragility through non-invasive imaging techniques that predict fracture risk. She is currently investigating the contribution of cortical and trabecular bone structure to proximal femoral strength in collaboration with Mary L. Bouxsein (Harvard Medical School, Boston, USA). She is a part of a comprehensive research consortium that aims to improve the management of patients with Gaucher disease - a genetic disorder with very variable manifestations but which causes disabling disease especially in the bones of the skeleton.

                       

With the great support of the National Osteoporosis Society along with support from the Bone Research Society I got the unique opportunity to be a visiting research fellow in Mary L. Bouxsein lab (BIDMC & Harvard Medical School, Boston). This experience gave me the opportunity to link two major themes of fracture prediction: the patient-based imaging with laboratory-based measures of bone mechanical properties. Furthermore, I was exposed to a variety of experimental techniques used to assess bone strength and widened my professional network which I believe will lead to collaboration in the future

Dr. Fjóla Jóhannesdóttir

Osteoporosis Conference 2016

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